Implanon NXT

Implanon NXT





Zuellig Pharma
Concise Prescribing Info
Dosage/Direction for Use
Subdermal insertion No preceding hormonal contraceptive use in the past mth Insert on day 1 & 5 of the menstrual cycle. Changing from combined oral contraceptive (COC), vag ring or transdermal patch Insert preferably on the day after last active COC tab, but at the latest on the day following the usual tab-free interval or last placebo COC tab. Changing from progestagen-only method [pill, injectable, implant or intrauterine system (IUS)] Injectable contraceptives: Insert when the next inj would be due. Pill: Insert w/in 24 hr any day after last pill. Implant or IUS: Insert on the same day of removal. Post 1st-trimester abortion Insert w/in 5 days following 1st trimester abortion or miscarriage. Post 2nd-trimester abortion Insert between day 21-28 following 2nd trimester abortion or miscarriage. Postpartum w/ breastfeeding Insert after 4th postpartum wk. Postpartum w/o breastfeeding Insert between 21-28 days postpartum.
Hypersensitivity. Active venous thromboembolic disorder, known or suspected sex steroid-sensitive malignancies, undiagnosed vag bleeding. History of benign or malignant liver tumours & severe hepatic disease. Known or suspected pregnancy.
Special Precautions
Discontinue use if thrombosis & sustained HTN develops. Not for protection against HIV (AIDS) & other STDs. Breast carcinoma; thrombotic & other vascular events; long-term immobilization due to surgery or illness; history of thromboembolic disorders; history of chloasma gravidarum; ovarian cysts. Complications of insertion; changes in menstrual bleeding pattern. Avoid sun exposure or UV radiation. Diabetic, hyperlipidemic & overwt women. Concomitant medications decreasing etonogestrel plasma conc. Liver disease. Ectopic pregnancy. Not to be used during pregnancy.
Adverse Reactions
Vag infection; headache; acne; breast pain & tenderness, irregular menstruation; increased wt. Increased appetite; affect lability, depression, nervousness, decreased libido; dizziness; hot flush; abdominal pain, nausea, flatulence; alopecia; dysmenorrhea, ovarian cyst; implant site pain & reaction, fatigue, flu-like illness, pain; decreased wt.
Drug Interactions
Decreased effectiveness w/ phenytoin, barbiturates, primidone, bosentan, carbamazepine, rifampicin, oxcarbazepine, topiramate, felbamate, griseofulvin, ritonavir, efavirenz, St. John's wort. Increased or decreased plasma conc w/ HIV PIs, NNRTIs, boceprevir, telaprevir. Increased serum conc w/ strong (eg, ketoconazole, itraconazole, clarithromycin) or moderate (eg, fluconazole, diltiazem, erythromycin) CYP3A4 inhibitors. Increased plasma & tissue conc of cyclosporin. Decreased plasma & tissue conc of lamotrigine.
MIMS Class
Depot Contraceptives
ATC Classification
G03AC08 - etonogestrel ; Belongs to the class of progestogens. Used as systemic contraceptives.
Implanon NXT implant 68 mg
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