Hypromellose

Intraocular
Adjunct in ophthalmic surgery

Ophthalmic
Dry eye

Patient w/ pre-existing glaucoma. Pregnancy and lactation.

Ophthalmologic: Mild stinging, blurred vision, eye pain, foreign body sensation, eye irritation, ocular hyperaemia, post-op transient increase in intraocular pressure.

Ophth: C

This drug may cause transient blurring of vision on instillation, if affected, do not drive or operate machinery. Remove contact lenses prior to admin and reinsert after 15 min.

Description:
Mechanism of Action: Hypromellose is a methyl and hydroxypropyl mixed ether of cellulose. It is used as artificial tears to prevent conjunctival and corneal damage due to impaired lacrimal secretions. It is also used as a visco-elastic agent by maintaining a deep chamber and allowing more efficient manipulation, hence, helps the vitreous face to be pushed back, thereby preventing formation of a post-operative flat chamber.

Store below 25°C. Protect from light.

Ophthalmic Lubricants

Anon. Hydroxypropyl Methylcellulose. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 12/07/2017.

Buckingham R (ed). Hypromellose. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 12/07/2017.

Genteal Severe Gel (Novartis Pharmaceutical Corporation). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 12/07/2017.

Goniovisc Ophthalmic Lubricant 2.5% Solution/Drops (HUB Pharmaceuticals, LLC). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 12/07/2017.

Joint Formulary Committee. Hypromellose. British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 12/07/2017.