Adult Herpes simplex infections 200 mg 5 times daily at 4-hrly intervals for 5 days.
Severe immunocompromised patient 400 mg 5 times daily.
Severe renal impairment 200 mg bd.
Suppression of herpes infections in immunocompetent patient 200 mg qds at 6-hrly intervals or 400 mg bd at 12-hrly intervals.
Prophylaxis of herpes simplex infections 200 mg qds at 6-hrly intervals.
Severely immunocompromised patient 400 mg qds.
Varicella & herpes zoster infections 800 mg 5 times daily at 4-hrly intervals for 7 days.
Severe renal impairment (CrCl <10 mL/min) Management of herpes simplex infections 200 mg bd at 12-hrly intervals.
Herpes zoster infections 800 mg bd at 12-hrly intervals.
Moderate renal impairment (CrCl 10-25 mL/min) Herpes zoster infections 800 mg tds at 8-hrly intervals.
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