Granodex

Granodex Dosage/Direction for Use

granisetron

Manufacturer:

Dexa Medica

Distributor:

Averroes Pharma
Full Prescribing Info
Dosage/Direction for Use
Chemotherapy induced nausea and vomiting (CINV): Adults: Prevention: A dose of 1-3 mg (10-40 mcg/kg) of granisetron should be administered either as a slow intravenous injection (over 30 seconds) or as an intravenous infusion diluted in 20 to 50 ml infusion fluid and administered over 5 minutes, prior to the start of chemotherapy.
Treatment: A dose of 1-3 mg (10-40 mcg/kg) granisetron should be administered either as a slow intravenous injection (over 30 seconds) or as an intravenous infusion diluted in 20 to 50 ml infusion fluid and administered over 5 minutes. Further treatment doses of granisetron may be administered, if required, at least 10 minutes apart. The maximum dose of granisetron to be administered over 24 hours should not exceed 9 mg.
Paediatrics: Prevention and treatment: A dose of 10-40 mcg/kg bodyweight (up to 3 mg) should be administered as an intravenous infusion, diluted in 10 to 30 ml infusion fluid and administered over 5 minutes prior to the start of chemotherapy. One additional dose may be administered within a 24 hours period if required. This additional dose should not be administered until at least 10 minutes after the initial infusion.
Radiotherapy induced nausea and vomiting (RINV): Adults: Prevention: A dose of 1-3 mg (10-40 mcg/kg) of granisetron should be administered either as a slow intravenous injection (over 30 seconds) or as an intravenous infusion diluted in 20 to 50 ml infusion fluid and administered over 5 minutes, prior to the start of radiotherapy.
Treatment: There is insufficient information to recommend the intravenous administration of granisetron in the treatment of RINV in adult patients.
Paediatrics: There is insufficient information to recommend intravenous administration of granisetron in the prevention and treatment of RINV in children.
Postoperative nausea and vomiting (PONV): Adults: Prevention: A dose of 1 mg (10 mcg/kg) of granisetron should be administered as a slow intravenous injection (over 30 seconds) prior to induction of anesthesia.
Treatment: A dose of 1 mg (10 mcg/kg) of granisetron should be administered by slow intravenous injection (over 30 seconds). The maximum dose for patients undergoing anesthesia for surgery is a total dose of 3 mg of granisetron intravenous in one day.
Paediatrics: There is insufficient information to recommend intravenous administration of granisetron in the prevention and treatment of postoperative nausea and vomiting in paediatric patients.
Special dosage instruction: Elderly: no dosage adjustment required.
Renal impairment: no dosage adjustment required.
Hepatic impairment: no dosage adjustment required.
Route of Administration: Intravenous injection or infusion.
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in