Fluprednidene


Generic Medicine Info
Indications and Dosage
Topical/Cutaneous
Corticosteroid-responsive dermatoses
Adult: As 0.1% cream or, 0.05 or 0.1% oint: Apply over affected areas as directed.
Contraindications
Application with occlusive dressings. Treatment of ulcerative conditions, rosacea. Indiscriminate use in pruritus.
Special Precautions
Risk of systemic absorption when applied to large areas, broken skin or under occlusive dressings. Pregnancy and lactation; elderly and child (long-term use).
Adverse Reactions
Hyperhidrosis, skin thinning and atrophy, dryness, irritation, epistaxis, loss of skin collagen, local hypopigmentation.
Potentially Fatal: Hypersensitivity reactions.
Drug Interactions
Reduced effects with barbiturates, carbamazepine, phenytoin, primidone, rifampicin. Excessive loss with thiazides, furosemide. Increase incidence of GI bleeding with NSAIDs. Decrease serum concentrations of salicylates. Decrease effect of antimuscarinics in myasthenia gravis. Increased requirements of antidiabetics and antihypertensives.
Action
Description:
Mechanism of Action: Fluprednidene is a corticosteroid with glucocorticoid activity.
MIMS Class
Topical Corticosteroids
Disclaimer: This information is independently developed by MIMS based on Fluprednidene from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2024 MIMS. All rights reserved. Powered by MIMS.com
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