Adult Acute exacerbation of chronic bronchitis 1 tab once daily for 5 days. Community-acquired pneumonia 1 tab once daily for 10 days. Acute bacterial sinusitis 1 tab once daily for 7 days. Mild to moderate pelvic inflammatory disease 1 tab once daily for 14 days. Complicated skin & skin structure infections IV therapy followed by 1 tab once daily for 7-21 days. Complicated intra-abdominal infection IV therapy followed by 1 tab once daily for 5-14 days.
View Flonoxin overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity to moxifloxacin or other quinolones. History of quinolone-related tendon disease/disorder. Congenital or documented acquired QT prolongation, electrolyte disturbances particularly in uncorrected hypokalaemia, clinically relevant bradycardia & heart failure w/ reduced left ventricular ejection fraction, previous history of symptomatic arrhythmias. Not to be used concurrently w/ QT interval-prolonging drugs. Hepatic impairment (Child-Pugh C), increased transaminase >5-fold ULN. Pregnancy & lactation. Patients <18 yr.
Hypersensitivity. Discontinue use if antibiotic-associated diarrhea & colitis; 1st sign of pain or inflammation occurs. Not recommended for patients w/ complicated pelvic inflammatory disease; MRSA infections. Patients w/ ongoing proarrhythmic conditions eg, acute myocardial ischaemia or QT prolongation; bullous skin reactions eg, SJS or TEN; CNS disorders, risk factors predisposing to seizures or lowering seizure threshold; sensory or sensorimotor polyneuropathy; psychosis or history of psychiatric disease; G6PD deficiency. Avoid use in patients w/ known history of myasthenia gravis. Monitor blood glucose in diabetic patients. Vision disorders. Maintain adequate fluid intake. Concomitant use w/ oral hypoglycemic agent or insulin. Avoid exposure to UV irradiation or strong sunlight. Interference w/ Mycobacterium spp culture test. Galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. May affect ability to drive or use machines. Fulminant hepatitis potentially leading to hepatic failure. Renal impairment. Elderly.
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