Felbinac


Generic Medicine Info
Indications and Dosage
Topical/Cutaneous
Pain and inflammation
Adult: For relief of rheumatic pain, pain of non-serious arthritic conditions, and soft tissue injuries: As 3% gel or 3.17% foam: Gently rub approx 1 inch (2.5 cm) of gel or 1.5 inches (4 cm) of foam over affected area(s) 2-4 times daily. Max: 25 g daily (irrespective of the size or number of affected areas). Review therapy after 14 days.
Contraindications
Hypersensitivity (including patients in whom attacks of asthma, urticaria or acute rhinitis are precipitated by aspirin or other NSAIDs). Pregnancy and lactation.
Adverse Reactions
Significant: Asthma, renal disease, anaphylaxis (application of large amount).
Nervous: Paraesthesia.
GI: GI disturbance, dyspepsia.
Resp: Bronchospasm, dyspnoea, wheezing.
Dermatologic: Pruritus, rash, dermatitis, angioedema, purpura, epidermal necrolysis, erythema multiforme, photosensitivity, application site reactions.
Patient Counseling Information
Avoid application to broken skin, contact w/ eyes or mucous membranes, use of occlusive dressings, and excessive exposure of treated area to sunlight.
Drug Interactions
Increased incidence of adverse reactions w/ aspirin or other NSAIDs.
Action
Description:
Mechanism of Action: Felbinac is the active metabolite of fenbufen. It is used topically for local treatment of pain and inflammation of the musculoskeletal system.
Pharmacokinetics:
Absorption: Topical application results in low circulating levels of felbinac.
Distribution: Distributed preferentially to site of inflammation.
Storage
Store below 25°C.
MIMS Class
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
ATC Classification
M02AA08 - felbinac ; Belongs to the class of non-steroidal antiinflammatory preparations for topical use. Used in the treatment of joint and muscular pains.
References
Buckingham R (ed). Felbinac. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 21/02/2017.

Joint Formulary Committee. Felbinac. British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 21/02/2017.

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