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Eslo

Eslo

escitalopram

Manufacturer:

Hetero Labs

Distributor:

Unimed
Concise Prescribing Info
Contents
Escitalopram
Indications/Uses
Major depressive episodes, panic disorder w/ or w/o agoraphobia, social & generalized anxiety disorder (SAD & GAD), obsessive-compulsive disorder (OCD).
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Dosage/Direction for Use
Major depressive episodes, SAD & GAD, OCD 10 mg once daily, may be increased to max: 20 mg daily. Panic disorder w/ or w/o agoraphobia Initially 5 mg for 1st wk before increasing to 10 mg daily. May be further increased up to max: 20 mg daily. Hepatic impairment, patient known to be poor CYP2C19 metabolisers Initially 5 mg daily for 1st 2 wk, may be increased to 10 mg daily.
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Overdosage
View Eslo overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Concomitant use w/ non-selective, irreversible MAOIs, pimozide.
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Special Precautions
Discontinue use if serotonin syndrome or increased seizure frequency occurs. Avoid use in patients w/ unstable or controlled epilepsy. History of suicide-related events, suicidal ideation. Paradoxical anxiety, history of mania/hypomania; diabetes; akathisia/psychomotor restlessness; known bleeding tendency. Not be used w/ MAOI or w/in 14 days of discontinuation; restart treatment at least 7 days after. Concomitant use w/ drugs causing hyponatraemia; St. John's wort; oral anticoagulant, drugs affecting platelet function eg, atypical antipsychotics, phenothiazines, TCAs, ASA, NSAIDs, ticlopidine, dipyridamole; electroconvulsive therapy. Avoid abrupt discontinuation. May affect ability to drive & use machines. Cirrhotic patients. Severe renal impairment (CrCl <30 mL/min). Pregnancy. Not recommended during lactation. Not to be used in childn & adolescents <18 yr. Elderly >65 yr.
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Adverse Reactions
Nausea. Decreased/increased appetite; anxiety, restlessness, abnormal dreams, decreased libido, female anorgasmia; insomnia, somnolence, dizziness, paraesthesia, tremor; sinusitis, yawning; diarrhoea, constipation, vomiting, dry mouth; increased sweating; arthralgia, myalgia; ejaculation disorder, male impotence; fatigue, pyrexia; increased wt.
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Drug Interactions
Serotonin syndrome w/ non-selective MAOIs; reversible, selective MAOI-A eg, moclobemide; irreversible MAOI-B eg, selegiline; serotonergic drugs eg, tramadol, sumatriptan, other triptans. Lowered seizure threshold w/ TCAs, SSRIs, neuroleptics (eg, phenothiazine, thioxanthenes, butyrophenones), mefloquine, bupropion, tramadol. Enhanced effects w/ lithium, tryptophan. Increased AR incidence w/ St. John's wort. Altered anticoagulant effects w/ oral anticoagulants. Increased bleeding tendency w/ NSAIDs. Increased plasma conc w/ omeprazole, cimetidine. Increased plasma levels of desipramine, metoprolol. Concomitant use w/ fluoxetine, fluvoxamine, lansoprazole, ticlopidine, flecainide, propafenone, clomipramine, nortriptyline, antipsychotics, CYP2C19-metabolized drugs, alcohol.
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Storage
View Eslo storage conditions for details to ensure optimal shelf-life.
Description
View Eslo description for details of the chemical structure and excipients (inactive components).
Action
View Eslo mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class
Antidepressants
ATC Classification
N06AB10 - escitalopram ; Belongs to the class of selective serotonin reuptake inhibitors. Used in the management of depression.
Presentation/Packing
Form
Eslo FC tab 10 mg
Packing/Price
10 × 10's;3 × 10's
Form
Eslo FC tab 20 mg
Packing/Price
10 × 10's;3 × 10's
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