IM Adult ≥20 yr 20 mcg dose. Neonate, infant & childn up to & including 19 yr 10 mcg dose. Childn 11-15 yr 20 mcg at 0, 6 mth or 3-dose accelerated schedule of 10 mcg. Renal insufficiency/undergoing hemodialysis ≥16 yr 4 double dose at elected date 1, 2 & 6 mth from date of 1st dose, ≤15 yr, including neonate 10 mcg at 0, 1, 2 & 12 mth or 0, 1 & 6 mth. Known or presumed HBV exposure 1st dose at 0, 1, 2-12 mth. Neonate born of HBV-carrier mother 10 mcg starting at birth at 0, 1, 2 & 12 mth or 0, 1 & 6 mth.
Anaphylactic reactions. Not to be inj intravascularly, intradermally or into buttocks. Not for protection against infection caused by other pathogens infecting the liver eg, hepatitis A, C & E virus. Postpone vaccination in patients w/ acute severe febrile illness. Syncope. Resp monitoring for 48-72 hr in very premature infants (≤28 wk of gestation) & w/ previous history of resp immaturity. Patients w/ HIV infection & impaired immune system. Renal insufficiency eg, haemodialysis. Pregnancy & lactation.
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