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Duovent

Duovent

ipratropium + fenoterol

Manufacturer:

Boehringer Ingelheim

Distributor:

DKSH
Concise Prescribing Info
Contents
Per 4 mL Ipratropium Br 0.5 mg, fenoterol HBr 1.25 mg
Indications/Uses
Symptomatic prevention & treatment of chronic obstructive airway disorders w/ reversible airflow limitation eg, bronchial asthma & especially chronic bronchitis w/ or w/o emphysema. Concomitant anti-inflammatory therapy considered for patients w/ bronchial asthma & steroid-responsive COPD.
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Dosage/Direction for Use
Adult, elderly & adolescent >12 yr Acute bronchospasm episodes 1 unit-dose vial. Very severe cases 2 unit-dose vials.
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Overdosage
View Duovent overdosage for action to be taken in the event of an overdose.
Contraindications
Hypersensitivity to fenoterol HBr or atropine-like substances. Hypertrophic obstructive cardiomyopathy, tachyarrhythmia.
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Special Precautions
Hypersensitivity. Discontinue use if paradoxical bronchospasm occurs. Patients predisposed to narrow-angle glaucoma; insufficiently controlled DM, recent MI, severe organic heart or vascular disorders, hyperthyroidism, phaeochromocytoma, pre-existing urinary outflow tract obstruction eg, prostatic hyperplasia or bladder-neck obstruction; underlying severe heart disease eg, ischaemic heart disease, arrhythmia or severe heart failure; hypokalaemia; cystic fibrosis; acute, rapidly worsening dyspnoea. Avoid contact w/ eyes. Positive doping test result. Prolonged use. Concomitant use w/ other sympathomimetic bronchodilators. May affect ability to drive & use machines. Pregnancy & lactation. Not recommended in childn ≤12 yr.
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Adverse Reactions
Cough, dry mouth, headache, tremor, pharyngitis, nausea, dizziness, dysphonia, tachycardia, palpitations, vomiting, increased systolic BP, nervousness.
Drug Interactions
Enhanced bronchodilatatory effects w/ other β-adrenergics, anticholinergics, xanthine derivatives eg, theophylline. Potentially serious reduction in bronchodilatation w/ β-blockers. Increased β2-agonist induced hypokalaemia w/ xanthine derivatives, corticosteroids, diuretics. Increased susceptibility to arrhythmias w/ digoxin. Enhanced β-adrenergic agonists action w/ MAOIs or TCAs. Increased susceptibility on CV effects of β-agonists w/ halogenated hydrocarbon anaesth eg, halothane, trichloroethylene, enflurane. Not recommended in co-administration w/ other anticholinergic drugs.
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Caution For Usage
For caution against possible variation of physical aspect of medicine... Click to view Duovent detailed prescribing information
Storage
View Duovent storage conditions for details to ensure optimal shelf-life.
Description
View Duovent description for details of the chemical structure and excipients (inactive components).
Action
View Duovent mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class
Antiasthmatic & COPD Preparations
ATC Classification
R03AL01 - fenoterol and ipratropium bromide ; Belongs to the class of combination of adrenergics with anticholinergics, that may also include a corticosteroid. Used in the treatment of obstructive airway diseases.
Presentation/Packing
Form
Duovent inhalation soln (unit-dose vial)
Packing/Price
4 mL x 60 × 1's
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