Clevudine: Indication, Dosage, Side Effect, Precaution

This information is not country-specific. Please refer to the Malaysia prescribing information.

Generic Medicine Info

Indications and Dosage

Oral
Chronic hepatitis B

Adult: 30 mg once daily, for up to 24 wk.

Action

Description:
Mechanism of Action: Clevudine is a L-thymidine analogue that is a substrate for 3 intracellular enzymes, namely, cytoslic thymidine kinase, cytosolic deoxycytidine kinase and mitochondrial deoxypyrimidine kinase. It interferes with hepatitis B viral cell replication by inhibiting the activity of viral DNA polymerase and reverse transcriptase.

MIMS Class

Antivirals

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