Symptoms and treatment for overdose and antidote(s): Acute overdosage: In the event of acute, excessive oral overdosage, reversible renal toxicity has been reported in some cases. Therefore, apart from routine emergency measures, it is recommended to monitor renal function.
Treatment: Since there is no specific antidote for ciprofloxacin overdose, treatment should be symptomatic and supportive and may consist of the following: To decrease absorption: Induction of emesis or use of gastric lavage to evacuate the stomach to eliminate unabsorbed drug; Administration of Mg- or Ca-containing antacids.
Specific treatment: Maintenance of adequate hydration.
Only a small amount of ciprofloxacin (<10%) is removed from the body after hemodialysis or peritoneal dialysis.