Tab Usual duration: 7 days (range: 5-10 days).
Adult & adolescent >13 yr Most infections 250 mg bd.
Mild to moderate lower resp tract infection eg, bronchitis 250 mg bd.
More severe lower resp tract infections eg, pneumonia 500 mg bd.
UTI 125 mg bd.
Pyelonephritis 250 mg bd.
Gonorrhoea 1 g as single dose.
Childn Usual dose: 125 mg bd.
Acute otitis media Childn >2 yr 250 mg bd.
IM/IV inj Adult 0.75 g 8 hrly.
Severe, complicated infections 1.5 g 6-8 hrly.
Bacterial meningitis Max: 3 g 8 hrly.
Uncomplicated gonorrhoea 1.5 g IM as single dose at 2 separate sites w/ oral probenecid 1 g.
Surgical prophylaxis 1.5 g pre-op & 0.75 g IV/IM 8 hrly.
Prophylaxis in open heart surgery 1.5 g IV at anaesth induction & 12 hrly thereafter for total: 6 g.
Infant & childn >3 mth 50-100 mg/kg daily in divided doses 6-8 hrly.
More severe infection 100 mg/kg daily.
Bacterial meningitis Initially 200-240 mg/kg daily IV in divided doses 6-8 hrly.