Control of hyperphosphataemia in adult patients receiving haemodialysis or peritoneal dialysis, or chronic kidney disease (CKD) not on dialysis w/ serum P ≥1.78 mmol/L.
Patient not taking phosphate binder Initially 1 or 2 tab tds based on serum P level. CKD patient on dialysis or patient switching from sevelamer HCl Max: 14 g daily.
Dysphagia, swallowing disorders, severe GI motility disorders including untreated or severe constipation or major GI tract surgery. Monitor bicarbonate, Cl levels during treatment; additional monitoring of fat-soluble vit & folic acid in patients undergoing peritoneal dialysis. Assess vit A, D, E & K status regularly. Not recommended in patients w/ CKD not on dialysis w/ serum P <1.78 mmol/L. Pregnancy & lactation. Not recommended in childn <18 yr.
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