Cardura/Cardura XL Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Doxazosin mesylate

Indications/Uses

HTN & initial agent to control BP. In hypertensive or normotensive patients w/ benign prostatic hyperplasia (BPH) & reduced urinary flow associated w/ BPH.

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Dosage/Direction for Use

Cardura tab HTN Initially 1 mg once daily for 1 or 2 wk, may be increased to 2 mg once daily for additional 1 or 2 wk. If needed, increase dose gradually at similar intervals to 4 mg, 8 mg & 16 mg. BPH Initially 1 mg once daily, may be increased to 2 mg & thereafter to 4 mg & up to max 8 mg w/ 1-2 wk intervals. Cardura XL CR tab Initially 4 mg once daily, may be increased to 8 mg once daily after 4 wk.

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Overdosage

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Administration

May be taken with or without food: Cardura XL: Swallow whole, do not chew/crush/divide.

Contraindications

Hypersensitivity to doxazosin, quinazolines. Pregnancy & lactation.

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Special Precautions

Postural hypotension/syncope. Intraoperative Floppy Iris Syndrome. Priaprism. Concomitant use w/ PDE-5 inhibitors. May affect ability to drive & use machines. Hepatic impairment. Pregnancy & lactation. Cardura XL CR tab Preexisting severe GI narrowing.

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Use In Pregnancy & Lactation

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Adverse Reactions

Vertigo, nausea, edema, asthenia, fatigue, malaise, dizziness, headache, postural hypotension, somnolence, syncope, rhinitis. Cardura XL CR tab Peripheral edema, abdominal & back pain, myalgia, bronchitis. HTN: Palpitation, tachycardia, dry mouth, chest pain, coughing, pruritus, cystitis, urinary incontinence. BPH: Dyspepsia, flu-like symptoms, resp tract infection, UTI, somnolence, dyspnea, hypotension.

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Drug Interactions

Symptomatic hypotension w/ PDE-5 inhibitors. Strong CYP3A4 inhibitors eg, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir, saquinavir, telithromycin or voriconazole.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Cardura/Cardura XL detailed prescribing information

Storage

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Description

View Cardura/Cardura XL description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Drugs for Bladder & Prostate Disorders / Other Antihypertensives

ATC Classification

C02CA04 - doxazosin ; Belongs to the class of alpha-adrenoreceptor antagonists, peripherally-acting antiadrenergic agents. Used in the treatment of hypertension.

Regulatory Classification

Presentation/Packing

Form

Cardura XL CR tab 4 mg

Packing/Price

100's

Form

Cardura tab 2 mg

Packing/Price

100's

Cardura/Cardura XL

doxazosin

Manufacturer:

Viatris

Distributor:

Zuellig Pharma