Bridion Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Sugammadex Na

Indications/Uses

Reversal of neuromuscular blockade induced by rocuronium or vecuronium.

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Dosage/Direction for Use

Routine reversal Adult Recommended dose: 4 mg/kg as single IV bolus inj if recovery has reached at least 1-2 post-tetanic counts (PTC) or 2 mg/kg as single IV bolus inj if spontaneous recovery has occurred up to at least the reappearance of T₂ following rocuronium- or vecuronium-induced blockade. Childn & adolescent 2-17 yr 2 mg/kg as single IV bolus inj at reappearance of T₂. Immediate reversal of rocuronium-induced blockade Adult 16 mg/kg as single IV bolus inj 3 min after bolus dose of rocuronium Br 1.2 mg/kg.

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Overdosage

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Contraindications

Hypersensitivity.

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Special Precautions

Hypersensitivity reactions. Not be used for reversal of neuromuscular blockade induced by steroidal neuromuscular blockers other than rocuronium or vecuronium. Recurrence of neuromuscular blockade; light anesth; marked bradycardia. Delayed recovery time in CV disease, oedematous stage. Monitor resp function during recovery. Carefully monitor coagulation parameters in patients w/ known coagulopathies. ICU setting; patients on controlled Na diet. Not recommended in severe renal impairment including patients requiring dialysis. Severe hepatic impairment; hepatic impairment accompanied by coagulopathy. Pregnancy & lactation. Not recommended in term newborn infants & infants. Delayed recovery time in elderly.

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Use In Pregnancy & Lactation

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Adverse Reactions

Airway anesth complication, anesthetic complication, procedural hypotension & complication; cough; hypersensitivity; dysgeusia

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Drug Interactions

Potentially affected efficacy w/ toremifene, IV fusidic acid. Potentially affect efficacy of hormonal contraceptives.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Bridion detailed prescribing information

Storage

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Description

View Bridion description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Antidotes & Detoxifying Agents

ATC Classification

V03AB35 - sugammadex ; Belongs to the class of antidotes. Used to reverse neuromuscular blockade caused by rocuronium or vecuronium.

Regulatory Classification

Presentation/Packing

Form

Bridion soln for inj (vial) 100 mg/mL

Packing/Price

2 mL x 10 × 1's;5 mL x 10 × 1's

Bridion

sugammadex

Manufacturer:

Merck Sharp & Dohme

Distributor:

Zuellig Pharma