Brexin Contraindications

Do not take Brexin: If the patient is allergic/hypersensitive to piroxicam or to any of the excipients of BREXIN; if the patient previously had a stomach or intestinal ulcer, bleeding or perforation; if the patient currently have stomach or intestinal ulcer, bleeding or perforation; if the patient has or has had a history of gastrointestinal disorders (inflammation of the stomach or intestines) that predispose to bleeding disorders such as ulcerative colitis, Crohn's disease, gastrointestinal cancers, diverticulitis (inflamed or infected pouches/pockets in the colon); if the patient is taking other NSAIDs, icluding selective inhibitors of COX-2 and acetyl-salicylic acid (a substance present in many medicines used to relieve pain and lower fever). Remember that many NSAIDs can be purchased without medical prescription; if the patient is taking anticoagulants, such as warfarin, to prevent blood clots; if the patient previously had a serious allergic drug reaction to piroxicam, other NSAIDs and other medications, especially serious skin reations (regardless of severity) such as multiform erythema, exfoliative dermatitis (intense reddening of skin, with skin peeling off in scales or layers), vesiculo-bullous reactions: Stevens-Johnson syndrome, a condition with red blistered, eroded, bloody or crusted skin, and toxic epidermal necrolysis, a disease with blistering and peeling of the top layer of the skin; if the patient had symptoms of asthma, rhinitis, nasal polyposis, angioedema or rash during treatment with acetyl-salicylic acid or other NSAIDs; if the patient is suspected to be pregnant; if the patient is breast-feeding; if the patient is aged less than 18 years; if the patient has a severe hepatic disease; if the patient has moderate or severe heart failure; if the patient has blood alterations; if the patient has hemorrhagic diathesis (predisposition to frequent bleeding).
If any of these applies to the patient, BREXIN should not be given. Tell the doctor immediately.