Brexin

Brexin Adverse Reactions

piroxicam beta-cyclodextrin

Manufacturer:

Chiesi

Distributor:

Germax
Full Prescribing Info
Adverse Reactions
As all medicines, BREXIN may cause undesirable effects, although not all has that. BREXIN is better tolerated than plain piroxicam at gastro-intestinal level; in fact, the reduced permanence of the active ingredient in the gastro-intestinal tract reduces the risk of irritation due to direct contact.
Withdraw immediately treatment with BREXIN and contact the doctor: if there is development of skin blisters, reddening or desquamation (skin rash), ulceration in any part of the body (for example skin, mouth, eyes, lips or tongue), or any other sign of allergic reaction, such as skin rash, swelling of the face, lips or tongue, that may cause difficulty in breathing; skin or the white part of the eyes are yellow coloured (jaundice); signs of stomach bleeding, such as passing black or bloodstained bowel movements, or vomiting blood.
Most common effects: Ulcers of the digestive tract and gastrointestinal bleeding; nausea, vomiting, diarrhoea, flatulence, constipation, gastric acidity, abdominal pain, ulcerative stomatitis, bowel inflammatory diseases (colitis and Crohn's disease); swelling of ankles, legs and feet (water retention); increase of blood pressure; heart failure (difficult breathing and tiredness).
Least common effects: Heart attack ("myocardial infarction"); stroke; anorexia; tiredness; anemia; skin blisters, reddening or desquamation (skin rash); ulceration in any part of the body (for example skin, mouth, eyes, lips or tongue), or any other sign of allergic reaction, such as skin rash, swelling of the face, lips or tongue, wheezing, yellow coloured skin or eyes (jaundice); increased normal parameters of hepatic function; pancreatitis; acute renal failure, blood in urine, difficult urination; increase of blood non-proteic nitrogen (increase of azotemia); swelling of ankles, legs and feet (water retention); increase of blood pressure (hypertension); nose bleeding; headache; sleepiness; hearing loss or buzzing in the ears; dizziness; sight disturbances; discomfort; blood or lymphatic alterations; gastritis.
Rare effects: Bruises occurrence; alteration of blood glucose parameters (hypo- and hyper-glycemia); sweating; body weight changes; insomnia; depression; swelling, blisters or skin desquamation; skin photosensitivity; dry mouth; erethism; impairment of bladder function; shock; hair loss; impairment of nails growth; fatal hepatitis.
Inform the doctor or pharmacist in case any of the undesirable effects is worsening or if any unwanted effect, if not described previously, occurs.
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