Boostrix

Boostrix

Manufacturer:

GlaxoSmithKline

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Per 0.5 mL Diphtheria toxoid not <2 IU, tetanus toxoid not <20 IU, Bordetella pertussis antigens (pertussis toxoid 8 mcg, filamentous haemagglutinin 8 mcg, pertactin 2.5 mcg)
Indications/Uses
Booster vaccination against DPT for individuals 4 yr onwards. Passive protection against pertussis in early infancy following maternal immunisation during 2nd- or 3rd-trimester of pregnancy.
Dosage/Direction for Use
0.5 mL single dose by deep IM inj.
Contraindications
Hypersensitivity to vaccine or after previous inj. Encephalopathy of unknown aetiology occurring w/in 7 days following previous vaccination w/ pertussis-containing vaccine. Transient thrombocytopenia or neurological complications following earlier vaccination against diphtheria &/or tetanus.
Special Precautions
Anaphylactic reaction. Not to be inj IV. Postpone vaccination in patients w/ acute severe febrile illness. Temp ≥40°C; collapse or shock-like state; persistent, inconsolable crying lasting ≥3 hr occurring w/in 48 hr of vaccination; convulsions w/ or w/o fever occurring w/in 3 days of vaccination. Thrombocytopenia or bleeding disorder; history of convulsions, family history of adverse event following vaccination; syncope. Immunosuppressed patients. Pregnancy & lactation. Defer pertussis immunization in childn w/ progressive neurological disorders.
Adverse Reactions
Inj site pain, redness & swelling, fatigue; headache. GI disorders; fever ≥37.5°C. Adults, adolescents & childn 10 yr onwards: Malaise. Dizziness; inj site mass & sterile abscess. Childn 4-9 yr: Irritability; somnolence. Anorexia.
Drug Interactions
Adequate immunologic response may not be achieved w/ immunosuppressants.
MIMS Class
Vaccines, Antisera & Immunologicals
ATC Classification
J07AJ52 - pertussis, purified antigen, combinations with toxoids ; Belongs to the class of pertussis bacterial vaccines.
Presentation/Packing
Form
Boostrix vaccine (inj) (pre-filled syringe) 0.5 mL
Packing/Price
0.5 mL x 1's
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