Cardiac disorders: AV-conduction disturbances, worsening of pre-existing heart failure, bradycardia.
Vascular disorders: Feeling of coldness or numbness in the extremities, hypotension, orthostatic hypotension.
Metabolism and nutrition disorders: Increased triglycerides.
Psychiatric disorders: Sleep disorders, depression, nightmares, hallucinations.
Nervous system disorders: Dizziness*, headache*, syncope.
Eye disorders: Reduced tear flow (to be considered if the patient uses lenses), conjunctivitis.
Ear and labyrinth disorders: Hearing disorders.
Respiratory disorders: Bronchospasm in patients with bronchial asthma or a history of obstructive airways disease, allergic rhinitis.
Gastrointestinal disorders: Gastrointestinal complaints such as nausea, vomiting, diarrhea, constipation.
Hepatobiliary disorders: Increased liver enzymes (ALAT, ASAT), hepatitis.
Skin and subcutaneous tissue disorders: Hypersensitivity reactions (itching, flush, rash), beta-blockers may provoke or worsen psoriasis or induce psoriasis-like rash, alopecia.
Musculoskeletal and connective tissue disorders: Muscular weakness and cramps.
Reproductive system disorders: Potency disorders (reduced libido).
General disorders: Fatigue*, asthenia.
*These symptoms especially occur at the beginning of the therapy. They are generally mild and often disappear within 1-2 weeks.