Beriate Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Human coagulation factor VIII

Indications/Uses

Treatment & prophylaxis of bleeding in patients w/ haemophilia A (congenital factor VIII deficiency).

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Dosage/Direction for Use

IV Early haemarthrosis, muscle or oral bleeding 20-40 IU/dL every 12-24 hr for at least 1 day until bleeding is resolved or healing is achieved. More extensive haemarthrosis, muscle bleeding or haematoma 30-60 IU/dL every 12-24 hr for ≥3-4 days until pain & acute disability are resolved. Life-threatening haemorrhage 60-100 IU/dL every 8-24 hr until threat is resolved. Minor surgery including tooth extraction 30-60 IU/dL every 24 hr for at least 1 day until healing is achieved. Major surgery (pre- & post-op) 80-100 IU/dL every 8-24 hr until adequate wound healing, then continue for at least another 7 days. Long-term prophylaxis 20-40 IU/kg at 2-3 days interval.

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Overdosage

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Contraindications

Hypersensitivity.

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Special Precautions

Discontinue use if hypersensitivity occurs. Monitor for development of neutralising Ab (inhibitors). Substitution therapy in patients w/ existing CV risk factors. Risk of central venous access device-related complications eg, local infections, bacteraemia & catheter site thrombosis. Transmission of infectious agents. Appropriate hepatitis A & B vaccination for patients in regular/repeated receipt of human plasma-derived factor VIII products. Patients on controlled Na diet. Pregnancy & lactation.

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Use In Pregnancy & Lactation

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Adverse Reactions

Factor VIII inhibition in previously-untreated patients.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Beriate detailed prescribing information

Storage

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Description

View Beriate description for details of the chemical structure and excipients (inactive components).

Action

View Beriate mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Haemostatics

ATC Classification

B02BD02 - coagulation factor VIII ; Belongs to the class of blood coagulation factors. Used in the treatment of hemorrhage.

Regulatory Classification

Presentation/Packing

Form

Beriate powd for inj 1,000 IU

Packing/Price

1's

Form

Beriate powd for inj 250 IU

Packing/Price

1's

Form

Beriate powd for inj 500 IU

Packing/Price

1's

Beriate

factor viii

Manufacturer:

CSL Behring

Distributor:

DKSH