Not to be used as inj. Not for hemostasis & sealing in situations where a fast sealant clotting is required. Not recommended for laparoscopic surgery. Not for use in neurosurgery & suture support for GI or vascular anastomoses. Hypersensitivity, allergies to bovine proteins. Soft tissue inj. Application using pressurized air or gas. Excessive clot thickness may negatively interfere w/ efficacy & wound healing process. Monitor changes in BP, pulse, O2 saturation & end tidal CO2. Ensure sufficient protection/cover to parts outside the designated application area to prevent tissue adhesion at undesired sites. Discontinue use if any hypersensitivity reactions occur. Perform selection of donors, screening of individual donations & plasma pools for specific markers of infection & inclusion of effective manufacturing steps for inactivation/removal of viruses to prevent transmitting infections. Parvovirus B19 infection in pregnant women & individuals w/ immunodeficiency or increased erythropoiesis eg, hemolytic anemia. Concurrent use w/ oxycellulose-containing prep as carrier materials. Pregnancy & lactation. Patients >65 yr.