Adalat LA must not be used in cases of known hypersensitivity to nifedipine or to any of the excipients (see Excipients/Inactive Ingredients under Description).
Nifedipine is contraindicated in pregnancy before week 20 and during breastfeeding (see Use in Pregnancy & Lactation).
Adalat LA must not be used in cases of cardiovascular shock.
Adalat LA must not be used in patients with Kock pouch (ileostomy after proctocolectomy).
Nifedipine must not be used in combination with rifampicin because no efficient plasma levels of nifedipine may be obtained due to enzyme induction (see Interactions).