BeneFIX

BeneFIX

Manufacturer:

Pfizer
Concise Prescribing Info
Contents
Nonacog α (recombinant coagulation factor IX)
Indications/Uses
Control & prevention of hemorrhagic episodes & for routine & surgical prophylaxis in patients w/ hemophilia B (congenital factor IX deficiency or Christmas disease) including control & prevention of bleeding in surgical settings.
Dosage/Direction for Use
IV Bleeding & surgery Major 50-100 IU/dL, repeat infusion every 12-24 hr for 7-10 days. Moderate 25-50 IU/dL, repeat infusion every 12-24 hr until bleeding stops & healing begins about 2-7 days. Minor 20-30 IU/dL, repeat infusion every 12-24 hr for 1-2 days. Prophylaxis Previously treated adult 40 IU/kg (13-78 IU/kg) at 3- to 4-day intervals.
Contraindications
Hypersensitivity to nonacog α or hamster proteins.
Special Precautions
Hypersensitivity. Activity-neutralizing Ab (inhibitors); thrombosis; nephrotic syndrome; CV events. Pregnancy & lactation.
Adverse Reactions
Headache, cough, vomiting, pyrexia. Factor IX inhibition, hypersensitivity, dizziness, dysgeusia, phlebitis, hypotension, flushing, nausea, rash, urticaria, chest discomfort, infusion-site reaction & pain.
MIMS Class
Haemostatics
ATC Classification
B02BD04 - coagulation factor IX ; Belongs to the class of blood coagulation factors. Used in the treatment of hemorrhage.
Presentation/Packing
Form
BeneFIX powd for inj 1,000 IU
Packing/Price
(+ 5 mL solvent in pre-filled syringe) 1's
Form
BeneFIX powd for inj 250 IU
Packing/Price
(+ 5 mL solvent in pre-filled syringe) 1's
Form
BeneFIX powd for inj 500 IU
Packing/Price
(+ 5 mL solvent in pre-filled syringe) 1's
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in