Rotate inj sites & do not inj into areas w/ tender, bruised, red, or hard skin. Discontinue treatment in case of serious or severe hypersensitivity reaction or severe constipation. Reports of development of HTN & worsening of pre-existing HTN. No safety data available in patients w/ certain major CV diseases. Avoid use during pregnancy. Consider use during breast-feeding only if clinically needed. Safety & efficacy in childn <18 yr have not yet been established. Latex-sensitive individuals.
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